Changes in brain activity have been found in some studies of highly responsive hypnotic subjects. These changes vary depending upon the type of suggestions being given.[168][169] The state of light to medium hypnosis, where the body undergoes physical and mental relaxation, is associated with a pattern mostly of alpha waves[170] However, what these results indicate is unclear. They may indicate that suggestions genuinely produce changes in perception or experience that are not simply a result of imagination. However, in normal circumstances without hypnosis, the brain regions associated with motion detection are activated both when motion is seen and when motion is imagined, without any changes in the subjects' perception or experience.[171] This may therefore indicate that highly suggestible hypnotic subjects are simply activating to a greater extent the areas of the brain used in imagination, without real perceptual changes. It is, however, premature to claim that hypnosis and meditation are mediated by similar brain systems and neural mechanisms.[172]

Abnormal results can occur in instances where amateurs, who know the fundamentals of hypnosis, entice friends to become their experimental subjects. Their lack of full understanding can lead to immediate consequences, which can linger for some time after the event. If, for example, the amateur plants the suggestion that the subject is being bitten by mosquitoes, the subject would naturally scratch where the bites were perceived. When awakened from the trance, if the amateur forgets to remove the suggestion, the subject will continue the behavior. Left unchecked, the behavior could land the subject in a physician's office in an attempt to stop the itching and scratching cycle. If the physician is astute enough to question the genesis of the behavior and hypnosis is used to remove the suggestion, the subject may experience long-term negative emotional distress and anger upon understanding exactly what happened. The lack of full understanding, complete training, and supervised experience on the part of the amateur places the subject at risk.
Something I hear a lot from clients is, "I've tried everything, but I just feel hopeless." Another client I worked with suffered from Irritable Bowel Syndrome (IBS) for several years. She also struggled with her weight as she tried to find the source of what was causing the pain she had suffered daily. Her motivation and mood were at an all time low, and she was almost at the point where she had given up hope.

At the outset of cognitive behavioural therapy during the 1950s, hypnosis was used by early behaviour therapists such as Joseph Wolpe[71] and also by early cognitive therapists such as Albert Ellis.[72] Barber, Spanos, and Chaves introduced the term "cognitive-behavioural" to describe their "nonstate" theory of hypnosis in Hypnosis, imagination, and human potentialities.[35] However, Clark L. Hull had introduced a behavioural psychology as far back as 1933, which in turn was preceded by Ivan Pavlov.[73] Indeed, the earliest theories and practices of hypnotism, even those of Braid, resemble the cognitive-behavioural orientation in some respects.[69][74]
Yoga practice involves postures, breathing exercises, and meditation aimed at improving mental and physical functioning. Some practitioners understand yoga in terms of traditional Indian medicine, with the postures improving the flow of prana energy around the body. Others see yoga in more conventional terms of muscle stretching and mental relaxation.
The Federal Dictionary of Occupational Titles describes the job of the hypnotherapist: "Induces hypnotic state in client to increase motivation or alter behavior patterns: Consults with client to determine nature of problem. Prepares client to enter hypnotic state by explaining how hypnosis works and what client will experience. Tests subject to determine degree of physical and emotional suggestibility. Induces hypnotic state in client, using individualized methods and techniques of hypnosis based on interpretation of test results and analysis of client's problem. May train client in self-hypnosis conditioning. GOE: 10.02.02 STRENGTH: S GED: R4 M3 L4 SVP: 7 DLU: 77"[8]